Common Side Effects

Name: Common Side Effects
Genre: Animation, Drama, Comedy, Sci-Fi & Fantasy
Released: 2025-02-02
Rating: 8.5
Cast: Dave King, Emily Pendergast, Mike Judge, Martha Kelly, Joseph Lee Anderson

RETURNING2 Seasons10 Episodes★ 8.5

Common Side Effects is an animated drama series on Adult Swim that premiered in 2025, with 2 seasons and 10 episodes to date. The next episode, Season 2 Episode 1, airs on Jan 24, 2027.

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NetworkAdult Swim

First AiredFeb 2, 2025

Last AiredMar 30, 2025

GenreAnimation, Drama, Comedy, Sci-Fi & Fantasy

Runtime23 min

Created ByJoseph Bennett, Steve Hely

LanguageEnglish

CountryUnited States

ProductionBandera Entertainment, Green Street Pictures, Williams Street

Former high school lab partners Marshall and Frances begin to unravel a conspiracy involving big pharma and the federal government to suppress knowledge of a rare mushroom that may hold the key to curing all the world’s diseases.

NEXT EPISODE

S2 E1Episode 1Jan 24, 202788d

WHERE TO WATCH

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Cast

Dave King

Marshall Cuso (voice)

Emily Pendergast

Frances Applewhite (voice)

Mike Judge

Rick Kruger (voice)

Martha Kelly

Agent Harrington (voice)

Joseph Lee Anderson

Agent Copano (voice)

Seasons & Episodes2 seasons · 11 episodes

0% complete

E1Pilot

Feb 2, 202522m★ 7.7

Marshall meets his old high school classmate Frances and lets her in on a world-changing secret.

E2Lakeshore Limited

Feb 2, 202523m★ 7.5

Marshall's forced on the run as the DEA pursues him.

E3Hildy

Feb 9, 202523m★ 7.9

Marshall visits an old mentor as new pressures mount.

E4Dumpsite

Feb 16, 202523m★ 7.6

Frances tracks down Marshall in an unlikely location.

E5Star-Tel-Lite

Feb 23, 202522m★ 7.1

Marshall, Frances, and their crazy neighbors deal with the aftermath of a dangerous incident.

E6In the System

Mar 2, 202523m★ 7.5

Stuck in jail, Marshall faces new threats.

E7Blowfish

Mar 9, 202523m★ 7.4

A chance encounter offers a risky opportunity for escape.

E8Amelia & Wyatt

Mar 16, 202522m★ 7.2

Marshall and his new ally make a bold move.

E9Cliff's Edge

Mar 23, 202523m★ 7.6

Marshall's mushroom project grows out of hand.

E10Raid

Mar 30, 202523m★ 7.9

Dangerous forces converge on Marshall's camp.

About Common Side Effects

Common Side Effects is an animation, drama, comedy, sci-fi & fantasy series on Adult Swim. The show first aired on Feb 2, 2025 and currently has 2 seasons and 10 episodes. Common Side Effects is currently airing; the next episode airs on Jan 24, 2027. It has a rating of 8.5/10 based on 364 votes. The cast includes Dave King, Emily Pendergast, Mike Judge, Martha Kelly, Joseph Lee Anderson. Created by Joseph Bennett and Steve Hely.